What we do

We are a competence center in bioinformatics with a multidisciplinary team of scientists and technical staff. Our mission is to provide bioinformatics support to life science projects in Switzerland and abroad through scientific collaborations with academic and industry partners. Services and expertise we offer include algorithm development and optimization, software engineering, data management including database expertise (Oracle certified), data analysis (genomics, transcriptomics, proteomics, metabolomics, lipidomics), development of web-based data mining and visualisation tools and in silico modelling.

Core facility activities

The key services provided as part of our core facility activities are listed here.

Highlights 2018

Vital-IT continues to provide data management solutions and analysis expertise for several Innovative Medicine Initiative (IMI) projects in the diabetes area: RHAPSODY, BEAt-DKD, HypoRESOLVE. We continue to develop innovative solutions for hospitals to manage and analyze patient genetic data in collaboration with the Clinical Bioinformatics group: OncoBench is routinely used by the molecular pathology department of the Geneva University Hospital (HUG). For the AneuX SystemsX project, we developed an online tool for integration and analysis of clinical, imaging, and morphological modeling data on intracerebral aneurisms, collected from patients in multiple hospitals. We have developed MetaboGSE, a tool enabling interpretation of transcriptomics data in the context of metabolic networks. We have been closely collaborating with the Ludwig Cancer Research Institute on several projects including a pilot clinical trial testing a personalized vaccine for ovarian cancer, published in 2018.

Find out more about the Group’s activities

Main publications 2018

  • Tran VDT et al.
    Condition-specific series of metabolic sub-networks and its application for gene set enrichment analysis.
    Bioinformatics
  • Bekkar A et al.
    Expert curation for building network-based dynamical models: a case study on atherosclerotic plaque formation.
    Database
  • Tanyi JL et al.
    Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer.
    Sci Transl Med.

Members

epfl lausanne

Mark Ibberson
Vital-IT
University of Lausanne
Group Webpage

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Domains of activity:

  • Core facility and competence centre
  • Data management
  • Data mining
  • Genome reconstruction
  • Machine learning
  • Mass spectrometry
  • Next generation sequencing
  • Personalised medicine
  • Software engineering
  • Structural biology
  • Systems biology

Domains of application:

  • Basic research
  • Medicine and health

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