MAPACHE: A flexible pipeline to map ancient DNA
DNA found in remains can tell us more about extinct species and how individuals lived in ancient civilizations. However, the level of degradation of this ancient DNA as well as the risk of contamination makes mapping of whole genomes a difficult process. In this in silico talk, Samuel Neuenschwander from the SIB group of Anna-Sapfo Malaspinas at the University of Lausanne introduces MAPACHE, a workflow which enables mapping of ancient DNA to assemble genomes efficiently and reproducibly. This was published in the journal, Bioinformatics. If you are interested in working with ancient DNA or other samples of DNA that need to be mapped, then this in silico talk is for you.
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Neuenschwander S. et al., Mapache: a flexible pipeline to map ancient DNA, Bioinformatics 2023