Measuring inbreeding and its consequences on fitness is central for many areas in biology including human genetics and the conservation of endangered species. However, there is no consensus on the best method, neither for quantification of inbreeding itself nor for the model to estimate its effect on specific traits.

In this video, you will discover how introducing a mixed model with an allele-sharing-based relatedness matrix into inbreeding depression calculation allows for a more efficient estimation in structured populations.If you are a biologist or bioinformatician who needs to estimate the inbreeding depression in a group of related individuals, then this talk is for you!

About the in silico talks series – The latest in bioinformatics by SIB Scientists

The in silico talks online series aims to inform bioinformaticians, life scientists and clinicians about the latest advances led by SIB Scientists on a wide range of topics in bioinformatics methods, research and resources. Stay abreast of the latest developments, get exclusive insights into recent papers, and discover how these advances might help you in your work or research, by subscribing to the in silico talks mailing list.