What we do

Our group is located in the Department of Biomedicine (DBM) at the University of Basel. We collaborate with scientists from DBM on projects covering a broad spectrum of research topics, from cellular differentiation and evolutionary biology to the identification of a molecular basis for various human diseases. To do this, we focus on the analysis, interpretation and visualization of expression, epigenetic and genomic data, which are mainly derived from next-generation sequencing experiments.

Find out more about the Core Facility's activities

Main publications 2017

  • Alberti-Servera L et al. Single-cell RNA sequencing reveals developmental heterogeneity among early lymphoid progenitors. EMBO J. 2017 Dec 15;36(24):3619-3633.
  • Diepenbruck M et al. miR-1199-5p and Zeb1 function in a double-negative feedback loop potentially coordinating EMT and tumour metastasis. Nat Commun. 2017

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Members

University basel

Robert Ivanek
DBM Bioinformatics Core Facility
University of Basel and University Hospital Basel
Group Webpage

Domains of activity:

  • Core facility and competence centre
  • Biostatistics
  • Epigenetics
  • Functional genomics
  • Single-cell biology
  • Software engineering
  • Systems biology
  • Transcriptomics

Domain of application:

  • Basic research

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