What we do

In the Evolutionary Bioinformatics Group, we are interested in animal genome evolution with a focus on questions arising from evolutionary developmental biology (Evo-Devo). For this, we develop methods and databases to extract reliable information from genome and transcriptome data. Our main project is Bgee, a database for gene expression expertise. While developing Bgee, we conduct research on ontologies, biocuration, and statistical methods for transcriptomics. Our biological focus is to link Evo-Devo with evolutionary genomics. Notably, we study the role of gene duplication in the divergence between genes and between species.

Find out more about the Group’s activities

Main publications 2021

  • Liu J et al.
    The hourglass model of evolutionary conservation during embryogenesis extends to developmental enhancers with signatures of positive selection
    Genome Res, 10.1101/gr.275212.121
  • Bastian F et al.
    The Bgee suite: integrated curated expression atlas and comparative transcriptomics in animals
    Nucleic Acids Res, 10.1093/nar/gkaa793
  • Jaron K S et al.
    Genomic Features of Parthenogenetic Animals
    J Heredity, 10.1093/jhered/esaa031