What we do

In the Bioinformatics Unravelling Group of the University of Fribourg (BUGFri), we support life science researchers by providing expertise in data analysis of next-generation sequencing experiments, or any large-scale biological experiment requiring bioinformatics resources. We focus on genome assembly, annotation and comparison, as well as on mutant and structure variant identification by resequencing. We also perform metagenomics, RNAseq and ChIPseq data analysis, proteome clustering and ortholog/paralog classification, as well as pathway and gene set enrichment analysis.

Find out more about the Group’s activities

Core facility activities

Here are some of the key services we provide (also see here):

  • Project planning and grant writing;
  • Software testing and development;
  • Data management plan (DMP) and deposition in OpenData repositories;
  • Data analysis;
  • Training.

Main publications 2018

  • Aguilar-Bultet L et al.
    Genetic separation of Listeria monocytogenes causing central nervous system infections in animals.
    Front Cell Infect Microbiol.
  • Thoms M et al.
    Suppressor mutations in Rpf2-Rrs1 or Rpl5 bypass the Cgr1 function for pre-ribosomal 5S RNP-rotation.
    Nat Commun.
  • Babatunde KA et al.
    Malaria infected red blood cells release small regulatory RNAs through extracellular vesicles.
    Sci Rep.


university fribourg

Laurent Falquet
Bioinformatics Unravelling Group (BUGFri)
University of Fribourg
Group Webpage

Domains of activity:

  • Core facility and competence centre
  • Genes and genomes
  • Comparative genomics
  • Core facilities and competence centres
  • Data management
  • Data mining
  • Data visualisation
  • Epigenetics
  • Metagenomics
  • Microbiology
  • Transcriptomics
  • Workflows

Domains of application:

  • Agriculture
  • Basic research
  • Medicine and health