What we do

In the Bioinformatics Unravelling Group of the University of Fribourg (BUGFri), we support life science researchers by providing expertise in data analysis of next-generation sequencing experiments, or any large-scale biological experiment requiring bioinformatics resources. We focus on genome assembly, annotation and comparison, as well as on mutant and structure variant identification by resequencing. We also perform metagenomics, RNAseq and ChIPseq data analysis, proteome clustering and ortholog/paralog classification, as well as pathway and gene set enrichment analysis.

Find out more about the Group’s activities

Core facility activities

Here are some of the key services we provide (also see here):

  • Project planning and grant writing;
  • Software testing and development;
  • Data management plan (DMP) and deposition in OpenData repositories;
  • Data analysis;
  • Training.

Main publications 2019

  • Akarsu H et al.
    TASmania: A Bacterial Toxin-Antitoxin Systems Database
    PLoS Comput Biol, doi: 10.1371/journal.pcbi.1006946
  • Akarsu H et al.
    deltaRpkm: An R Package for a Rapid Detection of Differential Gene Presence Between Related Bacterial Genomes
    BMC Bioinformatics, doi: 10.1186/s12859-019-3234-2
  • Agüero JA et al.
    Large-Scale Comparison of Toxin and Antitoxins in Listeria monocytogenes
    Toxins (Basel), doi: 10.3390/toxins12010029


university fribourg

Laurent Falquet
Bioinformatics Unravelling Group (BUGFri)
University of Fribourg
Group Webpage

Domain(s) of activity:

  • Genes and genomes
  • Comparative genomics
  • Data management
  • Data mining
  • Data visualisation
  • Deep sequencing data
  • Epigenetics
  • Genome reconstruction
  • Metagenomics
  • Microbiology
  • Training

Domain(s) of application:

  • Agriculture
  • Basic research
  • Medicine and health