What we do

In the Molecular Allergology group we are aiming to unravel the molecular basis of allergic diseases, antigen presentation, immunotherapies, immunotolerance and tolerance breakage with a combination of functional genomics techniques, including proteomics, peptidomics and immunopeptidomics. With proteomics we also aim at identifying cellular proteotypes associated with immune system regulation, and to identify allergens in various food samples. The acquired large-scale molecular data are analysed with the aim to identify molecular markers with which risk factors, different disease phenotypes, their underlying pathogenic mechanisms, and different patient response groups can be distinguished.

Find out about the Group’s activities

Main publication 2021

  • Bates A E et al.
    Global COVID-19 lockdown highlights humans as both threats and custodians of the environment
    Biological conservation, 10.1016/j.biocon.2021.109175
  • Kern U et al.
    Impact of DJ-1 and Helix 8 on the Proteome and Degradome of Neuron-Like Cells
    Cells, 10.3390/cells10020404
  • Ogulur I et al.
    Advances and highlights in biomarkers of allergic diseases
    Allergy, 10.1111/all.15089

Members

davos

Katja Bärenfaller
Molecular Allergology Group
SIAF (University of Zurich), Davos
Group Webpage

Domain(s) of activity:

  • Proteins and proteomes
  • Biomarkers
  • Data mining
  • Functional genomics
  • Gene regulation
  • Immunology
  • Machine learning
  • Mass spectrometry
  • Peptidomics
  • Proteomics
  • Transcriptomics

Domain(s) of application:

  • Medicine and health

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