What we do

In the Swiss-Prot Group, we develop, annotate and maintain the UniProtKB/Swiss-Prot protein sequence database, the most widely used protein information resource in the world (and an ELIXIR Core Data Resource), as well as a number of other internationally renowned expert-curated knowledge resources. These include the HAMAP and PROSITE databases of protein families and domains, the ENZYME database of enzyme nomenclature, the Rhea database of biochemical reactions, the SwissLipids database of lipid structures and biological knowledge, and the ViralZone portal. The group also participates in the development and maintenance of the ExPASy website.

Highlights 2018

  • Rhea now used as the reference vocabulary for enzyme annotation in UniProt.
  • Launch of the Rhea SPARQL endpoint.

Find out more about the Group’s activities

Main publications 2018

  • Lombardot T et al.
    Updates in Rhea: SPARQLing biochemical reaction data.
    Nucl Acids Res.
  • UniProt Consortium
    UniProt: a worldwide hub of protein knowledge.
    Nucl Acids Res.
  • Lee K et al.
    Scaling up data curation using deep learning: An application to literature triage in genomic variation resources.
    PLoS Comput Biol.