Ioannis Xenarios
University of Lausanne
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What do we do?

With a multidisciplinary team of scientists and technical staff, at Vital-IT we maintain a competenc ecentre in bioinformatics and computational biology. Our infrastructure currently spreads across six institutions that maintain bio-technological platforms: SIB, the Universities of Geneva, Lausanne, Fribourg and Bern, and EPFL. At Vital-IT we enable scientists to access state-of-the-art computational infrastructure (processing, storage and archiving) as well as expertise in data analysis and algorithmic development.


The Vital-IT Group in Lausanne and the Swiss-Prot Group in Geneva provide unique and complementary resources to the community. Vital-IT provides computational infrastructure (computing and storage), software and bioinformatics analysis, whereas the Swiss-Prot Group provides biological knowledge (UniProtKB/Swiss-Prot, PROSITE, etc.).

Highlights 2017

Vital-IT has now become the Data Coordination Centre for several diabetes research activities within the Innovative Medicine Initiative (IMI-JU). Vital-IT has developed, with its partner the EMBO journal, an a novel data discovery tool recognized by its peers as an innovative platform in 2017. Vital-IT embeds over 2,400 bioinformatics-supporting software packages that enable reproducible science and data life cycle management. Vital-IT’s infrastructure supports several hundred research projects and maintains widely-used SIB resources, i.e. Swiss-Prot, MetaNetX, NeXtProt, OpenFlu, LipidX, SwissLipids, SwissDock, Swiss-Model and the ExPaSy portal. It also maintains more than 140 websites and services for its partner groups, with thousands of daily visitors.

Main publications 2017

  • Schmid-Siegert E et al. Low number of fixed somatic mutations in a long-lived oak tree. Nat plants, 3 (2017) doi: 10.1038/s41477-017-0066-9
  • Solimena M et al. Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes. Diabetologia (2017) doi: 10.1007/s00125-017-4500-3
  • Liechti R et al. SourceData: a semantic platform for curating and searching figures. Nat methods, 14 (2017) doi: 10.1038/nmeth.4471

Our main research topic: