What we do

The laboratory specializes in the development of computer-aided algorithms, programs and databases for protein engineering and drug design, with applications in oncology, notably in immunotherapy of cancer. We also provide support in Molecular Modeling for the Molecular Tumor Board of the Lausanne University Hospital.

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Main publications 2020

Krebs FA et al.
Trametinib Induces the Stabilization of a Dual GNAQ p.Gly48Leu- and FGFR4 p.Cys172Gly-Mutated Uveal Melanoma. The Role of Molecular Modelling in Personalized Oncology
Int J Mol Sci, 10.3390/ijms21218021

Chiffelle J et al.
T-cell repertoire analysis and metrics of diversity and clonality
Curr Opin Biotechnol, 10.1016/j.copbio.2020.07.010

Dheilly E et al.
Cathepsin S Protease Mediates T-Cell Response in Non-Hodgkin Lymphoma
Cancer Cell, 10.1158/2159-8290.CD-RW2020-066

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