Using high-throughput technologies, you can identify long lists of candidate genes that differ between two experimental conditions. In order to interpret these gene lists and to discover fundamental properties like gene function and disease relevance, you need to use the annotation linked to a given gene or protein sequence.
The goals of this course and the practical exercises that follow are to give some basic theoretical and practical knowledge on protein sequence databases with a focus on UniProtKB, on Gene Ontology, on the different manual and automated annotation pipelines (such as HAMAP) and, in particular, on the optimum use of UniProt. During the theory and the practical sessions, we will discuss questions such as:
This course targets biologists and bioinformaticians who seek to analyse protein data. It will also be useful for people who programmatically access protein sequence databases and need to understand the data.
Min 12 participants.
At the end of the course, the participants are expected to:
You are required to bring your own laptop with an Internet connexion.
09h15 Protein sequence databases
13h30 Automated annotation pipeline: theory and practicals
15h30 How to mine enzyme data: theory and practicals
The registration fees for academics are 60 CHF, and 300 CHF for industrial participants. This includes course content material and coffee breaks.
Deadline for registration and free-of-charge cancellation is set is set to 26 February 2020. Cancellation after this date will not be reimbursed. Please note that participation to SIB courses is subject to our general conditions.
You will be informed by email of your registration confirmation.
University of Lausanne (Metro M1 line, Sorge station). More details to the registered participants.
Coordination: Grégoire Rossier
We will recommend 0.25 ECTS credits for this course (given a passed exam at the end of the course).
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