What we do

The group is active in the fields of comparative genomics and shotgun metagenomics. We study molecular evolution, develop approaches to genomics data analyses, and implement computational pipelines. We apply evolutionary models to digest sequencing data, and revise these models using the novel data. We study functional genomic elements on the basis of sequence variability among different species and within populations. Our interests range from arthropod genomics, including invertebrate vectors of human pathogens, to the evolution of viruses and clinical microbiology.

The group develops the OrthoDB tool.

Find out about the Group’s activities

Main publications 2020

  • Seppey M et al.
    LEMMI: A continuous benchmarking platform for metagenomics classifiers
    Genome Res., 10.1101/gr.260398.119
  • Zdobnov E M et al.
    OrthoDB in 2020: evolutionary and functional annotations of orthologs
    Nucleic Acids Research, 10.1093/nar/gkaa1009
  • Manni M and Zdobnov E M
    Microbial contaminants cataloged as novel human sequences in recent human pan-genomes
    bioRxiv, 10.1101/2020.03.16.994376


University geneva

Evgeny Zdobnov & Evgenia Kriventseva
Computational Evolutionary Genomics Group
University of Geneva
Group Webpage

Domain(s) of activity:

  • Genes and genomes
  • Benchmarking
  • Comparative genomics
  • Evolutionary biology
  • Functional genomics
  • Infectious diseases
  • Machine learning
  • Metagenomics
  • Personalised medicine
  • Phylogeny
  • Software engineering

Domain(s) of application:

  • Agriculture
  • Basic research
  • Medicine and health