What we do

The group is active in the fields of comparative genomics and shotgun metagenomics. We study molecular evolution, develop approaches to genomics data analyses, and implement computational pipelines. We apply evolutionary models to digest sequencing data, and revise these models using the novel data. We study functional genomic elements on the basis of sequence variability among different species and within populations. Our interests range from arthropod genomics, including invertebrate vectors of human pathogens, to the evolution of viruses and clinical microbiology.

The group develops the OrthoDB tool.

Main publications 2018

  • Kriventseva EV et al.
    OrthoDB v10: sampling the diversity of animal, plant, fungal, protist, bacterial and viral genomes for evolutionary and functional annotations of orthologs.
    Nucleic Acids Res.
  • Seppey M et al.
    BUSCO: Assessing Genome Assembly and Annotation Completeness.
    Meth Mol Bio: Eukaryotic Gene Prediction
  • Rands CM et al.
    ACI-1 beta-lactamase is widespread across human gut microbiomes in Negativicutes due to transposons harboured by tailed prophages.
    Environ Microbiol.

Find out more about the Group’s activities

Members

University geneva

Evgeny Zdobnov
Computational Evolutionary Genomics Group
University of Geneva
Group Webpage

Domains of activity:

  • Genes and genomes
  • Benchmarking
  • Comparative genomics
  • Evolutionary biology
  • Functional genomics
  • Genome reconstruction
  • Infectious diseases
  • Metagenomics
  • Microbiology
  • Next generation sequencing
  • Phylogeny

Domains of application:

  • Agriculture
  • Basic research
  • Ecology
  • Medicine and health

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