What we do

The Applied Computational Genomics Team focuses on theoretical and computational aspects of modelling the process of genome evolution and adaptive change. With the growing size and complexity of molecular data, we strive to keep pace by providing accurate, scalable and practical computational solutions that enable a wide range of scientists to analyse patterns of evolution and natural selection in large genomic and omics data. We develop bioinformatic methods for real applications, ranging from biotechnology to biomedical research, ecology and agriculture.

More recently, we also worked on data integration as part of the NRP75 Bigdata project that aims at enabling sophisticated semantic queries across large, decentralized and heterogeneous databases via an intuitive interface.

As a follow-up of this project, we develop an automated Literature Based Discovery (LBD) system in the context of natural product drugs, using Semantic Web technologies.

Find out about the Group’s activities

Main publications 2020

Members

Zurich university waedenswil

Maria Anisimova
Applied Computational Genomics Team
Zurich University of Applied Sciences (ZHAW), Wädenswil
Group Webpage

Domain(s) of activity:

  • Evolution and phylogeny
  • Benchmarking
  • Biomarkers
  • Comparative genomics
  • Data mining
  • Evolutionary biology
  • Genome reconstruction
  • Machine learning
  • Phylogeny
  • Phylogenetic tree analysis (natural selection)
  • Semantic web format

Domain(s) of application:

  • Agriculture
  • Basic research
  • Medicine and health

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