What we do

We are dedicated to the processing, analysis and interpretation of next-generation sequencing data. We interact closely with research groups, and provide tailored comprehensive bioinformatics solutions. Additionally, we provide standard analysis pipelines for the most frequent research questions. We train researchers and bioinformaticians on various aspects of data analysis, and provide access to our computing infrastructure for running analyses.

Find out more about the Group’s activities

Core facility activities

Here are some of the key services we provide (also see here):

  • Next-generation data analysis;
  • Analysis of long reads;
  • Bioinformatics training;
  • Clinical genomics.

Main publications 2020

  • Ringel T et al.
    Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance
    Cell Stem Cell, 10.1016/j.stem.2020.02.007
  • Wang J et al.
    HLA-DR15 Molecules Jointly Shape an Autoreactive T Cell Repertoire in Multiple Sclerosis
    Cell, 10.1016/j.cell.2020.09.054
  • Walkowiak S et al.
    Multiple wheat genomes reveal global variation in modern breeding
    Nature, 10.1038/s41586-020-2961-x

Members

University zurich

Hubert Rehrauer
Functional Genomics Center Zurich (FGCZ)
ETHZ, University of Zurich
Group Webpage

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Domain(s) of activity:

  • Core facility and competence centre
  • Biomarkers
  • Biostatistics
  • Data management
  • Data mining
  • Deep sequencing data
  • Gene regulatory network analysis
  • Next generation sequencing
  • Single-cell biology
  • Software engineering
  • Transcriptomics

Domain(s) of application:

  • Basic research
  • Medicine and health

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