What we do

In the Bioinformatics Core Facility (BCF), we promote trans-disciplinary collaborations between research teams in medicine, molecular biology, genetics, genomics, statistics, and bioinformatics. In particular, we carry out analyses of biomedical-genomics data with a focus on biomarker studies in cancer research, building on our specific expertise in statistical methods for genomics data analysis. Recently, we have concentrated on molecular heterogeneity in cancer, colorectal cancer, single cells transcriptomics, genetic association studies, metagenomics and other new technologies. We are open to any kind of new research direction.

Core facility activities

The key services provided as part of our core facility activities are listed here.

Main publications 2019

  • Hendrikx S et al.
    Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2
    Cell Rep, doi: 10.1016/j.celrep.2019.01.016
  • Dangaj D et al.
    Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors
    Cancer Cell, doi: 10.1016/j.ccell.2019.05.004
  • Tsantoulis P et al.
    Prospective validation in epithelial tumors of a gene expression predictor of liver metastasis derived from uveal melanoma
    Sci Rep, doi: 10.1038/s41598-019-52841-y

Find out more about the Group’s activities

Members

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Mauro Delorenzi & Frédéric Schütz
Bioinformatics Core Facility (BCF)
University of Lausanne
Group Webpage

Domain(s) of activity:

  • Core facility and competence centre
  • Biomarkers
  • Data mining
  • Deep sequencing data
  • Mathematical modelling
  • Metagenomics
  • Next generation sequencing
  • Oncology
  • Single-cell biology
  • Transcriptomics

Domain(s) of application:

  • Basic research
  • Medicine and health

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