What we do

In the Bioinformatics Core Facility (BCF), we promote trans-disciplinary collaborations between research teams in medicine, molecular biology, genetics, genomics, statistics, and bioinformatics. In particular, we carry out analyses of biomedical-genomics data with a focus on biomarker studies in cancer research, building on our specific expertise in statistical methods for genomics data analysis. Recently, we have concentrated on molecular heterogeneity in cancer, colorectal cancer, single cells transcriptomics, genetic association studies, metagenomics and other new technologies. We are open to any kind of new research direction.

Core facility activities

The key services provided as part of our core facility activities are listed here.

Main publications 2018

  • Schütz F and Zollinger A
    ABPS: An R package for calculating the abnormal blood profile score.
    Front Physiol, doi: 10.3389/fphys.2018.01638
  • Nisa L et al.
    Comprehensive genomic profiling of patient-matched head and neck cancer cells: A preclinical pipeline for metastatic and recurrent disease.
    Mol Cancer Res, DOI: 10.1158/1541-7786.MCR-18-0056
  • Bady P et al.
    The DNA methylome of DDR genes and benefit from RT or TMZ in IDH mutant low-grade glioma treated in EORTC 22033.
    Acta Neuropathol, DOI: 10.1007/s00401-018-1810-6

Find out more about the Group’s activities

Members

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Mauro Delorenzi & Frédéric Schütz
Bioinformatics Core Facility (BCF)
University of Lausanne
Group Webpage

Domain(s) of activity:

  • Core facility and competence centre
  • Biomarkers
  • Data mining
  • Deep sequencing data
  • Mathematical modelling
  • Metagenomics
  • Next generation sequencing
  • Oncology
  • Single-cell biology
  • Transcriptomics

Domain(s) of application:

  • Basic research
  • Medicine and health

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