What we do

Our main task at the Bioinformatics Core Unit (BCU) is to support the research groups at the Institute of Oncology Research (IOR) with computational and statistical services. Our research interests are focused on the genetics and biology of cancer with a major emphasis on lymphomas and epithelial cancers, such as prostate, breast and ovarian cancer. Importantly, more than as just a supporting role, we proactively identify and develop novel bioinformatics projects that can complement and in many cases drive our biologic research.

Core facility activities

In addition to supporting the research groups at the Institute of Oncology Research (IOR) with computational and statistical services, we develop innovative data analysis tools, visualization software and database resources for genomics research in collaboration with the Dalle Molle Institute of Artificial Intelligence (IDSIA) and the SIB Swiss Institute of Bioinformatics.

Here are some of the key services we provide (also see here):

  • Biostatistical analyses;
  • Data mining;
  • Training.

Main publications 2018

  • Mensah AA et al.
    Bromodomain and extra-terminal domain inhibition modulates the expression of pathologically relevant microRNAs in diffuse large B-cell lymphoma.
    Haematologica
  • Bonnici V et al.
    cuRnet: an R package for graph traversing on GPU.
    BMC Bioinformatics
  • Ceriani L et al.
    Metabolic heterogeneity on baseline 18FDG-PET/CT scan is a predictor of outcome in primary mediastinal B-cell lymphoma.
    Blood

Find out more about the Group’s activities

Members

Bellinzona institute oncology

Luciano Cascione
Bioinformatics Core Unit
Institute of Oncology Research, Bellinzona
Group Webpage

Domains of activity:

  • Core facility and competence centre
  • Biostatistics
  • Drug resistance
  • Machine learning
  • Systems biology
  • Transcriptomics

Domain of application:

  • Medicine and health

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