What we do

In the CMPG Group, we develop new methodologies for the simulation and analysis of molecular polymorphisms within species, with a particular focus on humans. We also maintain the Arlequin software, a popular package for the analysis of multi-locus genetic diversity within and between populations, as well as statistical methods to reconstruct and infer evolutionary processes from genomic data (i.e. using the fastsimcoal2 program). The team focuses on the effect of range expansions on genomic and functional diversity, and the detection of signatures of adaptation and selection at the molecular level.

Find out more about the Group’s activities

Main publications 2020

  • Gilbert K J et al.
    Transition from Background Selection to Associative Overdominance Promotes Diversity in Regions of Low Recombination
    Current Biology, 10.1016/j.cub.2019.11.063
  • Bosshard L et al.
    Dissection of the mutation accumulation process during bacterial range expansions.
    BMC Genomics, 10.1186/s12864-020-6676-z
  • Marchi N and Excoffier L
    Gene flow as a simple cause for an excess of high‐frequency‐derived alleles
    Evolutionary Applications, 10.1111/eva.12998


University bern

Laurent Excoffier
Computational and Molecular
Population Genetics Group
University of Bern
Group Webpage

Domain(s) of activity:

  • Evolution and phylogeny
  • Comparative genomics
  • Evolutionary biology
  • Paleogenomics
  • Population genetics

Domain(s) of application:

  • Basic research
  • Ecology