What we do

In the CMPG Group, we develop new methodologies for the simulation and analysis of molecular polymorphisms within species, with a particular focus on humans. We also maintain the Arlequin software, a popular package for the analysis of multi-locus genetic diversity within and between populations, as well as statistical methods to reconstruct and infer evolutionary processes from genomic data (i.e. using the fastsimcoal2 program). The team focuses on the effect of range expansions on genomic and functional diversity, and the detection of signatures of adaptation and selection at the molecular level.

Find out more about the Group’s activities

Main publications 2018

  • Pouyet F et al.
    Background selection and biased gene conversion affect more than 95% of the human genome and bias demographic inferences.
    eLife, doi: 10.7554/eLife.36317
  • Gilbert KJ et al.
    Mutation load dynamics during environmentally-driven range shifts.
    PLoS Genetics, doi: 10.1371/journal.pgen.1007450
  • Peischl S et al.
    Relaxed Selection During a Recent Human Expansion.
    Genetics, doi: 10.1534/genetics.117.300551