What we do

We are interested in understanding the design constraints, robustness, and evolution of gene regulatory systems, particularly at the level of transcription, using both modeling and data-driven approaches.

Read "The hills and valleys of evolution” - an interview with Joshua L. Payne about his SIB Virtual seminar

Main publications 2018

  • Payne J L et al.
    RNA-mediated gene regulation is less evolvable than transcriptional regulation.
  • Aguilar-Rodriguez J et al.
    The architecture of an empirical genotype-phenotype map. Evolution

Find out more about the Group’s activities


eth zurich

Joshua Payne
Computational Biology Group
ETH Zurich
Group Webpage

Twitter button

Domains of activity:

  • Evolution and phylogeny
  • Evolutionary biology
  • Functional genomics
  • Gene regulation
  • Gene regulatory network analysis
  • Systems biology

Domain of application:

  • Basic research

Other interesting links