New insights into the molecular paths leading to type 2 diabetes

Thanks to a unique dataset from living donors, and innovative multi-omics analysis, an international research team led by investigators at the Paul-Langerhans-Institute Dresden (PLID), the SIB Swiss Institute of Bioinformatics and the Max-Planck-Institute (MPI) of Biochemistry has shed some light into the processes driving islet dysfunction.

Applying user-centred design in life science resources

If you are interested in making the most of your scientific website, database or software, learning how to convert user feedback into new developments is key. And putting the user at the centre was a key aspect of the redesign of Expasy, our user-friendly knowledge discovery portal for life science.

SNSF’s Optimus Agora prize 2021 goes to “In the light of evolution”

How to popularize evolution and phylogenetics? The new project “In the light of evolution” aims to foster greater public interest as well as a practical understanding of this fundamental but rather abstract theme.

MetaNetX/MNXref: A unified namespace for metabolic models

Capturing biological pathways is a massive database challenge: it implies representing metabolites in a way that is understandable to both humans and computers, and which enables their interconnection through the biochemical reactions they engage in.

When genetics makes ancient civilisations speak

Based on the analysis of ancient DNA, a study co-directed by SIB Group Leader Anna-Sapfo Malaspinas at the Department of Computational Biology of the University of Lausanne sheds light on the settlement of Greece during the Bronze Age.

A shortcut to the genetics of molecular circadian rhythm

Do you usually wake up feeling rested but not hungry? It may be the sign of a particularly large meal the evening before – or simply reflect the difference in circadian rhythm between your gut and brain.

Discover the SIB Remarkable Outputs 2020

Discover the SIB Remarkable Outputs 2020, a list of ‘must-read’ works by SIB Members produced in 2020 and selected by a committee of SIB Group Leaders and Researchers.

The eventful settlement history of South Pacific islands

An international research team has reconstructed the human settlement history of the South Pacific by sequencing a large number of genomes from this region. The results challenge current knowledge about the first settlement of the Vanuatu archipelago and Polynesia.