Torsten Schwede & Thierry Sengstag
University of Basel
Group Webpage

What do we do?

sciCORE is a centre of competence in scientific computing. It provides high-performance computing infrastructure, large-scale storage resources, scientific software and databases, server infrastructures and user support as well as know-how and expertise to scientific research groups. At sciCORE we provide a professional environment for scientific applications: from bioinformatics, computational chemistry, physics and systems biology to medicine and economics. In direct collaboration with scientific research groups, we help develop, deploy, operate and extend the computational tools required for performing modern life science and biomedical research. We operate the IT infrastructure for several SIB services, e.g. SWISS-MODEL and SwissRegulon.

Highlights 2016

In 2016, the sciCORE team consolidated its support to the Swiss life-science community: notably, we expanded our support to web resources developed at Agroscope (ZH) and the University Hospital Basel, and deployed a new storage service available for groups using instruments that produce large amounts of data, such as high-resolution microscopes. Our data-management consulting to research groups at the University of Basel and SwissTPH was also extended.
By the end of 2016, sciCORE support grew to about 115 groups at the University of Basel, SwissTPH and University Hospitals. Our team collaborates actively with the SIB Training Group by contributing to computing and data analysis courses for life scientists (about 500 students in 21 courses covering an introduction to Linux, R and Python programming, statistics, genomics data mining, etc...). On the national scale, sciCORE remains active in infrastructure and research projects such as the Data-Life Cycle Management project, the eScience team and SystemsX.

Main publications 2016

  • Badri ND et al. Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking. Science Advances 2016;2(9):e1600823.
  • Auffray C et al. Making sense of big data in health research: Towards an EU action plan. Genome Medicine 2016;8(1):71.
  • García-Senz D, Cabezón R, Domínguez I, Thielemann FK. Type Ia Supernovae: Can Coriolis Force Break the Symmetry of the Gravitational Confined Detonation Explosion Mechanism? The Astrophysical Journal 2016; Issue 2 (2016); 819:132.

Our research topics: