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SIB provides the necessary bioinformatics services and resource


SIB counts some 65 research and service groups and some 800 scientists.


SIB offers training in bioinformatics for the national and international scientific community.

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Common breast cancer mutation induces multipotency and tumour heterogeneity

Understanding how different cell populations arise within a tumour – so-called tumour heterogeneity – is widely regarded as a major challenge for cancer biology.

Mohamed Bentires-Alj and his group at the FMI have discovered how the most frequent mutation in human breast cancer leads to tumour heterogeneity. The PI3-kinase mutation forces cells back into a dedifferentiated, stem-like state from which tumours containing cells of various lineages can develop. These results have been published in Nature.
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