DBM Bioinformatics Core Facility
University of Basel and University Hospital Basel
What do we do?
Our group is located in the Department of Biomedicine (DBM) at the University of Basel. We collaborate with scientists from DBM on projects covering a broad spectrum of research topics, from cellular differentiation and evolutionary biology to the identification of a molecular basis for various human diseases. To do this, we focus on the analysis, interpretation and visualization of expression, epigenetic and genomic data, which are mainly derived from next-generation sequencing experiments.
Main publications 2017
- Alberti-Servera L et al. Single-cell RNA sequencing reveals developmental heterogeneity among early lymphoid progenitors. EMBO J. 2017 Dec 15;36(24):3619-3633.
- Diepenbruck M et al. miR-1199-5p and Zeb1 function in a double-negative feedback loop potentially coordinating EMT and tumour metastasis. Nat Commun. 2017