What do we do?
In the Chemical and Biological Systems Engineering Laboratory, we develop tools for systems modelling and the analysis of chemical and biological networks. Our mission is to create enabling theories and computational methods for the generation of systems insights, as well as for understanding and acquiring knowledge in chemical, biological and medical applications. Our research spans multiple length and time-scales of cell biology, from gene/ signalling/metabolic networks in single cells to the aging process in human and cell culture bioreactors in the pharmaceutical industry.
Main publications 2017
- Hutter S et al. Glycosylation flux analysis reveals dynamic changes of intracellular glycosylation flux distribution in Chinese Hamster Ovary fed-batch cultures. Metab. Eng. 2017; 43:9.
- Gunawan R and Hutter S. Assessing and resolving model misspecifications in metabolic flux analysis. Bioengineering 2017; 4:48.
- Liu Y and Gunawan R. Bioprocess optimization under uncertainty using ensemble modeling. J. Biotech. 2017; 244:34.