What do we do?
The Laboratory of Protein Design & Immunoengineering started in March 2015, at the EPFL. Currently, we have established both the computational and experimental branches of our research. Despite the short life of the LPDI we can perform all the computational and biochemical experimentation proposed in this study. We currently perform our computational calculations at the High Performance Computing facility at the EPFL. The experimental arm of the laboratory is prepared to perform molecular biology, protein expression and purification, and protein biophysical characterization.
Main publications 2017
- Matthews ML et al. Chemoproteomic profiling and discovery of protein electrophiles in human cells. Nat Chem, 9, 234-43. doi: 10.1038/nchem.2645 2017
- Parker CG et al. Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell, 168, 527-41. doi: 10.1016/j.cell.2016.12.029