Tag: phylogenetic tree analysis (natural selection)

  • A genome under influence: The faulty yardstick in genomics studies and how to cope with it

    References form the basis of our comprehension of the world: they enable us to measure the height of our children or the efficiency of a drug. But when such yardsticks are faulty, doubts are cast on all the measurements that derive from them.

  • Daniel Wegmann's group

    What we do When observing nature, it is easy to be impressed by the huge diversity seen on any biological scale. Our primary aim is to better understand the underlying evolutionary and ecological processes that have been shaping this diversity...

  • Harmful mutations and range expansion: computers got it right

    Organisms that are expanding their spatial range suffer from a drastic decrease of fitness over time due to the accumulation of harmful mutations. A study led by a team of scientists from the SIB Swiss Institute of Bioinformatics and the University...

  • How species arise: a mathematical answer

    Predicting when and how species arise is now possible with a new theoretical model using genome-wide data, developed by SIB researcher Simon Aeschbacher and colleagues. The study was published yesterday in the Proceedings of the National Academy of...

  • Jérôme Goudet's group

    What we do Our group's interest is focused on understanding how the interplay of population structure, trait architecture and selection can be disentangled. To this end, we use different approaches, from theory and the development of statistical...

  • Laurent Excoffier's group

    What we do In the Computational and Molecular Population Genetics (CMPG) Group, we develop new methodologies for the simulation and analysis of molecular polymorphisms within species, with a particular focus on humans. We also develop and maintain...

  • Marc Robinson-Rechavi's group

    What we do In the Evolutionary Bioinformatics Group, we are mainly concerned with determining the role of evolutionary innovation and constraint in animals. For this, we develop methods and databases to extract reliable information from genome and...

  • Maria Anisimova's group

    What we do The Applied Computational Genomics Team focuses on theoretical and computational aspects of modelling the process of genome evolution and adaptive change. With the growing size and complexity of molecular data, we strive to keep pace by...

  • Matthew Robinson's group

    What we do We develop and apply statistical methodologies to large human phenotype-genotype datasets, to address long-standing questions in population and quantitative genetics. These have improved the prediction accuracy of disease risk in...

  • Nicolas Salamin's group

    What we do We develop models and software to better understand the evolution of organisms and to test macroevolutionary hypotheses. We are looking at the ecological, genomic and morphological factors that constrain speciation and adaptation. We...

  • Robert Waterhouse's group

    What we do The group’s research is focused on elucidating interactions between gene evolution and gene function through developing computational approaches to interrogate evolutionary and functional genomics data. We are developing quantifications...

  • Sara Mitri's group

    What we do Our group focuses on studying social interactions in microbial communities and how they evolve. We follow an interdisciplinary approach, where we quantify and characterize interactions within small bacterial communities in the lab, and...

  • The genetic burden of pioneers

    Having a pioneer ancestor could explain the excess of harmful mutations observed in recently colonized areas of Quebec, a recent study shows. Using a unique combination of genomic and historical data, researchers from SIB at the University of Bern,...