Tag: medicine and health

  • ‘Bioinformatics for all’ in May: many happy faces

    Over 650 people, including school classes, took part in our outreach activities around bioinformatics on the occasion of the University of Lausanne Open House (Mystères de l’UNIL) and the Night of the Museums in Geneva, on 18-21 May. The two events...

  • "Institutions like SIB play a key role in supporting our country's leading position"

    At the occasion of SIB's 20th birthday, we asked Mauro Dell'Ambrogio, State Secretary for Education, Research and Innovation (SERI) what has made SIB eligible for federal funding over the past years, and how was Switzerland positioned...

  • "Personalized health, health tailor-made"

    Discover the story of the patients for whom personalized medicine is already a reality. A TV documentary invites you to follow them with a team of oncologists, pathologists, biologists and bioinformaticians, in their search for a treatment against...

  • "Science Fiction": Discover science in a different way

    Are researchers austere? Is bioinformatics arid? Judge for yourself, with this handsome book published by SIB to mark the Institute's 20th anniversary, thanks to the financial support of many sponsors.

  • A brief history of SIB

    With the creation of the SIB Swiss Institute of Bioinformatics in 1998, Switzerland made a historical move and positioned itself as a pioneer in the field of data science.

  • A gene increases the severity of common colds

    Researchers funded by the SNSF have discovered mutations that worsen respiratory infections among children. Their study explains the mechanism involved.

  • A thorough ‘catalogue’ of an aggressive type of childhood cancer

    Improving cancer precision therapy requires a greater ability to identify and describe groups of patients who share the same molecular and clinical particularities. An SIB Swiss Institute of Bioinformatics group recently played a pivotal role in...

  • Alan Bridge's group

    What we do In the Swiss-Prot Group, we develop, annotate and maintain the UniProtKB/Swiss-Prot protein sequence database, the most widely used protein information resource in the world (and an ELIXIR Core Data Resource), as well as a number of...

  • Amos Bairoch - Lydie Lane's group

    What we do We aim to use a combination of bioinformatics and experimental methodologies to increase knowledge about the function of the 20,000 protein-coding genes in the human genome. Our main mission is the development of neXtProt, a human...

  • Andreas Wagner's group

    What we do In the Evolutionary Systems Biology Group, we study the evolution and evolvability of biological systems at all levels of biological organization, from genes and genomes to biological networks and whole organisms. We develop...

  • Bart Deplancke's group

    What we do In the Laboratory of Systems Biology and Genetics (LSBG), we use high-throughput sequencing, single cell genomics, microfluidics, and computational approaches to decipher the regulatory code in Drosophila and mammals with a specific...

  • Bastien Chopard's group

    What we do In the Scientific and Parallel Computing (SPC) Group, we develop new algorithms and methods to better understand and/or predict various phenomena in biology. We focus on multiscale modelling and computing, high-performance computing,...

  • Bernd Rinn's group

    What we do Our group in Scientific IT Services (SIS) is an interdisciplinary bioinformatics and scientific IT group, which develops computational tools and services. We provide HPC infrastructure and services, improve and port scientific software,...

  • Bioinformatics capacity building in South Africa

    The development of expertise in bioinformatics and genomics among future African scientists is key for finding solutions to local health problems. However such training and courses often rely on powerful and complex infrastructure.

  • Bioinformatics, a Swiss pride - 20 years of service to the life sciences and health

    Whether we are retracing the history of our ancestors, designing new drugs or understanding what gives Swiss Gruyère its unique flavour, bioinformatics has become an essential discipline.

  • Bruno Correia's group

    What we do The Laboratory of Protein Design & Immunoengineering started in March 2015, at the EPFL. Currently, we have established both the computational and experimental branches of our research. Despite the short life of the LPDI we can...

  • Carlos-Andrés Peña-Reyes's group

    What we do With the advent of high-throughput technologies and clinical information systems, the life sciences and clinical sciences now produce very large amounts of data (big data). Our goal is to uncover hidden patterns in these data, as well...

  • Christophe Dessimoz's group

    What we do At the interface of biology and computer science, we seek to better understand evolutionary and functional relationships between genes, genomes and species. Key underlying questions are: How can we extrapolate current biological...

  • Clinical Bioinformatics

    Focus on the group’s purpose The group’s objectives are to harmonize and standardize clinical bioinformatics analysis pipelines for omics (and other high-throughput) data across hospitals in Switzerland. Fostering harmonization of clinical NGS...

  • Dagmar Iber's group

    What we do The Computational Biology Group (CoBi) develops computational models of developmental processes. We place a particular focus on mechanistic 4D image-based in silico models of organogenesis (mouse lung, kidney, pancreas, limb, brain,...

  • Daniel Stekhoven's group

    What we do The Clinical Bioinformatics Unit is the dry lab of the ETH Zurich core facility NEXUS Personalized Health Technologies. CBU offers customized bioinformatics and biostatistics services for projects in the field of biomedical research. We...

  • Daniel Wegmann's group

    What we do When observing nature, it is easy to be impressed by the huge diversity seen on any biological scale. Our primary aim is to better understand the underlying evolutionary and ecological processes that have been shaping this diversity...

  • David Gfeller's group

    What we do In the Computational Cancer Biology Group, our aim is to study the interactions between cancer and immune cells. To this end, we develop machine learning algorithms to analyse large-scale genomics and proteomics data. In particular, we...

  • Emmanouil Dermitzakis receives prestigious award

    SIB’s Group Leader Emmanouil Dermitzakis, Professor of Genetics in the Department of Genetic Medicine and Development (University of Geneva Medical School), was awarded the 2017 Bodossaki Foundation Scientific Award in the field of Biosciences...

  • Emmanouil Manolis Dermitzakis's group

    What we do Our group has a strong interest in population genomics and genetics of complex traits. We use various methodologies to understand the role of genetic variation in phenotypic variation and what fraction of genetic variation is harboured...

  • Erik van Nimwegen's group

    What we do Our main research interest in the Genome Systems Biology (GSB) Group is the study of genome-wide regulatory systems, in order to reconstruct them from high-throughput molecular data, understand and model how they have evolved, and...

  • Evgeny Zdobnov's group

    What we do The group is active in the fields of comparative genomics and shotgun metagenomics. We study molecular evolution, develop approaches to genomics data analyses, and implement computational pipelines. We apply evolutionary models to...

  • Fabio Rinaldi's group

    What we do The BioMeXT group specializes in Information Extraction from the biomedical literature and other textual sources. Information extraction consists in automatically extracting structured information from textual documents. We specialize...

  • Fat, a personal affair

    Thirteen percent of the world's population suffers from obesity. Obesity is a particularly complex multi-factor disease, and the direct cause of common conditions such as diabetes or hypertension, making it a major health issue.

  • First Certificate of Advanced Studies (CAS) in personalized molecular oncology

    The University Hospital of Basel is launching a CAS in personalized molecular oncology with the SIB Swiss Institute of Bioinformatics and the University Hospital of Lausanne. First of its kind in Switzerland, this training takes place at a key...

  • Focus on Clinical Bioinformatics: Bridging the gap between data science and medicine

    “Stick out your tongue and say... ‘omics’”.In addition to patients’ vital signs or eating habits, molecular profiling data is increasingly becoming part of the medical practitioners’ toolbox. But these ‘omics’ data pose novel challenges, for...

  • Frédérique Lisacek's group

    What we do In the Proteome Informatics Group (PIG), we are involved in software and database development for the benefit of the proteomics and glycomics communities. These resources are made available through the ExPASy server. Software tools...

  • From cancer evolution to personalized therapies

    Being able to predict the resistance or sensitivity of a tumour cell to a drug is a key success-factor of cancer precision therapy. But such a prediction is made difficult by the fact that genetic alterations in tumours change dynamically over time...

  • From infrastructure planning to implementation, BioMedIT progresses

    Update on the Swiss Personalized Health Network (SPHN) Designed to promote the development of personalized health in Switzerland, the SPHN initiative will lay the foundations to foster research projects in this area, including mechanisms...

  • Giovanni Ciriello's group

    What we do The Computational Systems Oncology lab integrates algorithmic design, numerical modelling, and molecular biology approaches to address relevant questions in cancer biology and therapeutics. We explore single and combinations of genetic...

  • Gunnar Rätsch's group

    What we do We are interested in modern machine-learning techniques suitable for the analysis of problems that arise in medicine and biology. In particular, we develop new learning techniques that are capable of dealing with large amounts of...

  • Hubert Rehrauer's group

    What we do We are dedicated to the processing, analysis and interpretation of Next-Generation Sequencing data. We interact closely with research groups, and provide tailored comprehensive bioinformatics solutions. Additionally, we provide standard...

  • Igor Pivkin's group

    What we do Our research interests in the Scientific Computing Group lie in the area of multiscale/multiphysics modelling and parallel large-scale simulations of biological systems. We focus on the development of new computational models and...

  • Jacques Fellay's group

    What we do In the Host-Pathogen Genomics Group, we explore the genetic roots of inter-individual differences in response to infections, with a particular focus on the genomic interactions between pathogens and their human hosts. At the crossroads...

  • Joining forces against hypoglycaemia and diabetes

    Within the newly started European research project Hypo-RESOLVE, 23 leading international players from academia, industry and civil society - among which SIB's Vital-IT Group and the University of Lausanne - have joined forces to fight diabetes.

  • Jorg Stelling's group

    What we do We develop and apply computational and – most recently – experimental methods to analyse and design complex cellular networks, with a focus on large-scale mechanistic approaches. The group comprises biologists, computer scientists,...

  • Julia Vogt's group

    What we do The primary research interest of our group lies at the intersection of machine learning and medicine. We work on advancing and developing novel machine learning techniques for precision medicine, the life sciences and clinical data...

  • Karsten Borgwardt's group

    What we do Our lab acts as the bridge between big data analysis and biomedical research. We develop novel data mining algorithms to detect patterns and statistical dependencies in large datasets from the fields of biology and medicine. Our major...

  • Katja Baerenfaller'group

    What we do In the Molecular Allergology group we are aiming to unravel the molecular basis of allergic diseases, antigen presentation, immunotherapies, immunotolerance and tolerance breakage with a combination of functional genomics techniques,...

  • Laurent Falquet's group

    What we do In the Bioinformatics Unravelling Group of the University of Fribourg (BUGFri), we support life science researchers by providing expertise in data analysis of Next-Generation Sequencing (NGS) experiments, or any large-scale biological...

  • Luciano Cascione's group

    What we do Our main task at the Bioinformatics Core Unit (BCU) is to support the research groups at the Institute of Oncology Research (IOR) with computational and statistical services. Our research interests are focused on the genetics and...

  • Manfred Claassen's group

    What we do Our research in the Computational Single Cell Biology Group aims to elucidate the composition of heterogeneous cell populations and how these implement function in the context of cancer and immune biology. To accomplish this task, we...

  • Marc Robinson-Rechavi's group

    What we do In the Evolutionary Bioinformatics Group, we are mainly concerned with determining the role of evolutionary innovation and constraint in animals. For this, we develop methods and databases to extract reliable information from genome and...

  • Maria Anisimova's group

    What we do The Applied Computational Genomics Team focuses on theoretical and computational aspects of modelling the process of genome evolution and adaptive change. With the growing size and complexity of molecular data, we strive to keep pace by...

  • Mark Robinson's group

    What we do In the Statistical Bioinformatics Group, we develop robust data analysis solutions, including new or improved methods, for the analysis of genome-scale data. We develop statistical methods for interpreting data from high-throughput...