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SIB - Swiss Institute of Bioinformatics

SWISS BIOINFORMATICS

SIB NEWSLETTER - OCTOBER 2017

IN THIS ISSUE

Unlocking the genetic basis of our lifespan, mapping how alterations co-occur in tumours to improve precision therapy, explaining why common colds are not benign for all... None of these exciting ventures could be undertaken without the use of bioinformatics expertise, resources or infrastructure. Providing these to the scientific community around the world is one of SIB’s missions.
Find more on these topics in this October issue of Swiss Bioinformatics, plus: a look back on the recent Basel Computational Biology Conference [BC]2; another proof of the crucial role and relevance of biocuration; the latest SIB resources on lipids and viruses; upcoming training events and more.

TAKING THE PULSE OF SIB

[BC]2 conference: computational biology at its best

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Take a tour of the 13th annual Basel Computational Biology Conference, a key event of the year for the discipline, which brought together over 500 attendees on 12-15 September and was co-organized by SIB and the Biozentrum University of Basel …

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SIB for life scientists: discover what we can do for you

Whether you are a life scientist or a clinician, working in academia or the private sector, discover how SIB can support you at every step of your project to advance your research and make an impact on society…

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SIB, a national bioinformatics organizational model

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Long-term vision, external Scientific Advisory Board, training programmes… Learn more about the essential ingredients that contribute to making SIB a national model for other bioinformatics organizations, in a recent publication in Briefings in Bioinformatics...

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RESOURCES FOR THE LIFE SCIENCES

Part of SIB’s mission is to provide and maintain databases and software tools, which are of fundamental importance to the wider life-science community. These SIB Resources are regularly reviewed by SIB’s external Scientific Advisory Board to ensure they are best-in-class following a specific list of criteria, such as their impact. The Institute is committed to maintaining these core resources over the long term, to guarantee their access to life scientists worldwide.

New SIB bioinformatics resources for viruses and lipids

V-Pipe and SwissLipids are the latest additions to the ranks of SIB resources and are filling important gaps in the current landscape…

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Two SIB knowledgebases singled out at European level

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At the end of a stringent selection process led by ELIXIR, the intergovernmental organization that brings together life science resources from across Europe, two SIB data resources have been singled out as of crucial importance for life sciences: UniProtKB/Swiss-Prot and STRING…

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Expert curation is sustainable: the example of UniProtKB/Swiss-Prot

While the importance of knowledgebases is increasingly recognized, the question of their sustainability is frequently raised. A recent study led by Sylvain Poux, Head of Biocuration, and his colleagues from the SIB Swiss-Prot Group, reveals that…

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RESEARCH AT SIB

The 16 genetic markers that can cut a life story short

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The answer to how long each of us will live is partly encoded in our genome. Scientists from SIB, Lausanne University Hospital (CHUV), the University of Lausanne and EPFL have identified 16 genetic markers associated with a decreased lifespan, including…

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From cancer evolution to personalized therapies

Being able to predict the resistance or sensitivity of a tumour cell to a drug is a key success factor in cancer precision therapy. A recent study led by researchers at SIB, the University of Lausanne and EPFL provides…

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A gene increases the severity of common colds

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Colds that are not linked to influenza are generally benign. Even so, 2% of each generation of children have to go to hospital following a virulent infection. An international research collaboration coordinated by SIB and EPFL scientist Jacques Fellay has discovered…

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SIB TRAINING IN BIOINFORMATICS

Upcoming training events

There are still a few seats available in our popular “Statistics for Life Scientists” course from 11 to 14 December. Stay tuned for all upcoming courses (e.g. Proteomics application in immunoproteomics, Python for Life Scientists, NGS quality control, alignment and visualization) by joining the mailing list and checking out our training events page.

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SIB Training for the private sector at ILMAC, Lausanne

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On 4 and 5 October, SIB is presenting its activities and its training offer for the private sector at ILMAC, a leading Swiss fair for pharmaceuticals, chemicals and biotechnology.

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LATEST PROTEIN SPOTLIGHT

A touch of warmth

We need heat. All warm-blooded animals know this instinctively because when life leaves us, the cold creeps in fast. Heat is produced in different ways inside us, and not only to keep our body temperature at a healthy level but also to keep it stable. After the fashion of small mobile furnaces, we carry adipose tissues that are full of stored fat waiting to be burnt down to release heat – a process termed thermogenesis. Researchers have now discovered…

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