Latest Protein Spotlight: More to it

Multitasking is not limited to computers. On a day-to-day basis, humans frequently deal with more than one thing at a time - for the sake of speed, convenience and no doubt productivity. We brush our teeth while taking a shower, eat a sandwich while answering mails, wash the dishes while calling a relative. Though we are pretty good at it, humans are far from the only multitaskers on this planet. We also harbour a few inside us. Just consider cells... One cell can synthesize proteins, while secreting others, repairing its cytoskeleton and maintaining its membrane. And we now know that the odd protein is also able to juggle with more than one task - thus applying yet another layer of obsolescence to the not-so-old "one gene, one protein, one function" hypothesis. Such is the case for a protein known as dual function macrocyclase-peptidase, or POPB. POPB is involved in making amatoxins, which are very small cyclic peptides found in some mushrooms and particularly poisonous when ingested. Read more