Virus bioinformatics on the rise: SIB is among the founders of a dedicated European Centre

Most of today's bioinformatics is focused on bacteria and eukaryotic model organisms, while there is an urgent need for applying and developing computational approaches in the field of virology. With the founding of the European Virus Bioinformatics Centre (EVBC) in Jena, on 8 March 2017, by researchers from 10 European countries, the very best of European research from virology and bioinformatics has been brought together.

The Drug Design Workshop: tomorrow’s drugs at your fingertips

Bringing medicinal chemistry and bioinformatics to the layman, by using a didactic online platform based on professional tools, is the goal of the Drug Design Workshop. Developed in 2015 by SIB researchers, together with training and outreach officers, the workshop is both in English and French and has already successfully taken over 1,500 people, of all ages and background, on a journey to design/create the drugs of tomorrow.

SIB is part of a global coalition to sustain core data resources

The advancement of science, medicine and the society as a whole depends on crucial data resources, such as DNA sequence repositories or protein knowledgebases.
However the clock is ticking for most of these resources, as only a fraction benefit from long-term financial stability. Among the identified threats figure short-term funding, grant competition and shifting political priorities.

DNA, a (hyper)winding road

When it comes to packaging large amounts of information into tiny volumes, biology and physics often buddy up to reach creative solutions. The problem is even more complex with DNA, as the compacted information must also remain accessible to the proteins in charge of transcription.

Latest Protein Spotlight: A walk on the rough side

Life can be hard. There are times when you find yourself in the most unfriendly circumstances and, more often than not, the best way to deal with the situation is to find your own solution and wriggle your own way out. Living species are the most imaginative of beings when it comes to designing defence mechanisms.

Why am I shorter than you?

The answer to that question lies to some extent in our diet and environment, but mostly in our DNA (80%). Combining genome-wide association methods and an unmatched dataset of more than 700,000 participants, a recent study narrowed down the set of candidate changes to 83 variants, some of which altering the size by more than 2 cm.

Latest Protein Spotlight: Out of the ordinary

Life depends on chemical signals. Without them our heart wouldn't know how to beat or our thoughts how to form, our eyes would be unable to see, our legs unable to walk and our mouths would be incapable of speech.

SIB IN THE NEWS: DRUG DESIGN AND OUTREACH

Today in the national news, Marie-Claude Blatter (Responsible - SIB Outreach activities) and Vincent Zoete (Associate director - Molecular Modelling group) presented SIB's role in drug design and bioinformatics outreach on the Radio Télévision Suisse (RTS1). Watch the 8’13’’ broadcast here (in FR)!