In the 80s, Amos Bairoch - today Group Leader at SIB - felt the need to perfect an existing protein sequence databank. While working on his PhD, he started to “annotate” proteins by adding information such as their structure and pathological roles, and adapted the database to computers. Swiss-Prot, the manually annotated protein sequence database, was born! This was in 1986. At that time, the various versions were distributed on magnetic tapes...

Today, UniProtKB/Swiss-Prot is the most widely used protein information resource in the world. It provides concise, but thorough, descriptions of a non-redundant set of hundreds of thousands of proteins including their function, domain structure, post-translational modifications and variants. Its high-quality annotation is the fruit of manual expert curation by biologists who use information available in the scientific literature to provide an accurate description of each protein’s features. It is the fruit of an international consortium: the UniProt Consortium.

On the occasion of the Biocuration Conference 2016 in Geneva, the Swiss-Prot protein database celebrated its 30th Anniversary, these following pages are dedicated to this celebration and are retracing some of the SIB Swiss-Prot group’s history:

A brochure was also produced for the occasion, download it here