Torsten Schwede
Computational Structural Biology Group
University of Basel
Group Webpage

At the Computational Structural Biology (CSB) Group we are focusing on the development of methods and algorithms to model, simulate and analyse three-dimensional protein structures and their molecular properties in order to apply these techniques to understanding biological processes at a molecular level. Our main emphasis is on homology modelling approaches – using evolutionary information to model protein tertiary and quaternary structures. Applications in biomedical research include the study of protein-ligand interactions from different perspectives, such as the identification of small antiviral molecules to support drug development, the structure-guided engineering of enzymes or the interpretation of disease causing mutations in proteins.

Our research topics: