At the Evolutionary Bioinformatics Group we are mainly concerned with determining the role of evolutionary innovation and constraint in animals. For this, we develop methods and databases to extract reliable information from genome and transcriptome data. These databases include Bgee, a database for gene expression evolution, Selectome, a database of positive selection. In developing these resources, we also conduct research on ontologies, biocuration, and high-performance computing. Our biological focus is to link Evo-Devo with phylogenomics. We notably study the role of gene duplication in divergence between genes and between species.