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Hubert Rehrauer
Functional Genomics Center Zurich
ETHZ, University of Zurich
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What do we do?

We are dedicated to the processing, analysis and interpretation of Next-Generation Sequencing data. We interact closely with research groups, and provide tailored comprehensive bioinformatics solutions. We also provide standard analysis pipelines for the more frequent research questions. We train researchers and bioinformaticians on various aspects of data analysis, and provide access to our computing infrastructure for running analyses.

Highlights 2016

In 2016, we made our web-based NGS data analysis platform fully available for direct self-managed data exploration and analysis. With this convenient web access, researchers can leverage a comprehensive set of NGS analysis tools and an associated high-performance computing backend for their omics-related research. Additionally, thanks to our bioinformatics analysis we made a few key contributions towards a better understanding of disease mechanisms and potential theraupeutic options. Finally, with the use of long reads generated by FGCZ’s PacBio platform, we were able to contribute to various genome assemblies.

Main publications 2016

  • Hatakeyama et al. SUSHI: an exquisite recipe for fully documented, reproducible and reusable NGS data analysis. BMC Bioinformatics. 2016 Jun 2;17(1):228
  • Kulig et al. IL-12 protects from psoriasiform skin inflammation. Nat Commun. 2016 Nov 28;7:13466
  • Izuno et al. Genome sequencing of Metrosideros polymorpha (Myrtaceae), a dominant species in various habitats in the Hawaiian Islands with remarkable phenotypic variations. J Plant Res. 2016 Jul;129(4):727-36.

Our research topics: