Some viruses could be much older than previously thought, suggests a new study led by SIB scientists Moritz Saxenhofer and Gerald Heckel, from the University of Bern.
Being able to predict the resistance or sensitivity of a tumour cell to a drug is a key success-factor of cancer precision therapy. But such a prediction is made difficult by the fact that genetic alterations in tumours change dynamically over time and are often interdependent, following a pattern that is poorly understood.
The answer to how long each of us will live is partly encoded in our genome. Researchers have identified 16 genetic markers associated with a decreased lifespan, including 14 new to science.
Some proteins form a specific knot when they fold into their native structures. The function of knots in proteins and the mechanism of their formation are still poorly understood. In order to study protein knots, it is necessary to identify knotted proteins and also pinpoint the location of knotted regions.
The Swiss Personalized Health Network (SPHN) is a national initiative designed to promote the development of personalized health in Switzerland. As a part of it, the Data Coordination Centre, led by SIB under the supervision of the National Steering Board, will establish nationwide interoperability of molecular and clinical data to enable personalized health research.