Amos Bairoch & Lydie Lane
Computer and Laboratory Investigation of Proteins of Human Origin (CALIPHO)
Geneva, Centre Médical Universitaire (CMU)
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At the CALIPHO Group, which stands for “Computer and Laboratory Investigation of Proteins of Human Origin”, we aim to use a combination of bioinformatics and experimental methodologies to increase the knowledge about the function of the 20,000 or so protein-coding genes that exist in the human genome. Our main mission is the development of neXtProt, a human protein knowledge resource. Recently, we have focused on annotating the effects of human protein variations in the context of cancers and genetic diseases, and analysing results of high-throughput experiments to shed light on the function of selected sets of uncharacterized human proteins.

Our research topics: